{"id":2598,"date":"2020-11-16T10:59:30","date_gmt":"2020-11-16T10:59:30","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2598"},"modified":"2020-11-16T11:00:22","modified_gmt":"2020-11-16T11:00:22","slug":"anti-human-cd2-antibody-clone-rpa-2-10-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd2","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd2-antibody-clone-rpa-2-10-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd2\/","title":{"rendered":"Anti-Human CD2 Antibody, Clone RPA-2.10 Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD2"},"content":{"rendered":"

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Overview<\/h3>\n
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The RPA-2.10 antibody reacts with CD2, an ~50 kDa type I transmembrane glycoprotein and a member of the immunoglobulin (Ig) superfamily; two Ig-like domains are located in its extracellular portion. CD2 is broadly expressed on peripheral T and NK cells, dendritic cells, erythrocytes, most thymic T cells, subsets of thymic B cells, and on the endothelium. CD2 expression appears early during T cell differentiation. Aberrant expression has been observed in some lymphomas and myeloid leukemias. CD2 is critically important for T cell activation and signaling, as well as lymphocyte adhesion. The primary ligand for CD2 is CD58 (LFA-3) located on antigen-presenting cells, with additional ligands comprising CD15 (SSEA-1), CD48 and CD59. Notably, the RPA-2.10 antibody blocks the mixed lymphocyte reaction.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD2<\/div>\n<\/div>\n
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Alternative Names: LFA-2, SRBC-R, T11<\/div>\n<\/div>\n
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Reactive Species: Baboon; Capuchin Monkey; Cynomolgus; Pigtailed Macaque; Rhesus; Squirrel Monkey; Chimpanzee; Human; Pig<\/div>\n<\/div>\n
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Conjugation: APC; FITC; PE; PerCP<\/div>\n<\/div>\n
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Host Species: Mouse<\/div>\n<\/div>\n
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Cell Type: T Cells<\/div>\n<\/div>\n
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Application: Cell Isolation; Flow Cytometry; Functional Assay; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Western Blotting<\/div>\n<\/div>\n
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Area of Interest: Immunology<\/div>\n<\/div>\n
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Clone: RPA-2.10<\/div>\n<\/div>\n
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Gene ID: 914<\/div>\n<\/div>\n
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Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview The RPA-2.10 antibody reacts with CD2, an ~50 kDa type I transmembrane glycoprotein and a member of the immunoglobulin (Ig) superfamily; two Ig-like domains are located in its extracellular portion. CD2 is broadly expressed on peripheral T and NK cells, dendritic cells, erythrocytes, most thymic T cells, subsets of thymic B cells, and on the endothelium. CD2 expression appears early during T cell differentiation. Aberrant expression has been observed in some lymphomas and myeloid leukemias. CD2 is critically important for T cell activation and signaling, as well as lymphocyte adhesion. The primary ligand for CD2 is CD58 (LFA-3) located on antigen-presenting cells, with additional ligands comprising CD15 (SSEA-1), CD48 and CD59. Notably, the RPA-2.10 antibody blocks the mixed lymphocyte reaction. Subtype: Primary Antibodies Target Antigen: CD2 Alternative Names: LFA-2, SRBC-R, T11 Reactive Species: Baboon; Capuchin Monkey; Cynomolgus; Pigtailed Macaque; Rhesus; Squirrel Monkey; Chimpanzee; Human; Pig Conjugation: APC; FITC; PE; PerCP Host Species: Mouse Cell Type: T Cells Application: Cell Isolation; Flow Cytometry; Functional Assay; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Western Blotting Area of Interest: Immunology Clone: RPA-2.10 Gene ID: 914 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2573,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2598","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2598","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2573"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2598"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2598"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2598"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2598"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}