{"id":2607,"date":"2020-11-17T08:19:00","date_gmt":"2020-11-17T08:19:00","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2607"},"modified":"2020-11-17T08:19:00","modified_gmt":"2020-11-17T08:19:00","slug":"anti-beta-tubulin-iii-antibody-clone-tuj1-mouse-monoclonal-igg2a-antibody-against-human-mouse-rat-betatubulin-iii","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-beta-tubulin-iii-antibody-clone-tuj1-mouse-monoclonal-igg2a-antibody-against-human-mouse-rat-betatubulin-iii\/","title":{"rendered":"Anti-Beta-Tubulin III Antibody, Clone TUJ1 Mouse monoclonal IgG2a antibody against human, mouse, rat beta\u00adtubulin III"},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

Overview<\/h3>\n
\n
\n
The TUJ1 antibody reacts with beta-tubulin III, an ~50 – 55 kDa structural protein that is a component of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha and beta tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The TUJ1 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the C-terminal 15 amino acids of the protein.<\/div>\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n
\n
\n
\n
Subtype: Primary Antibodies<\/div>\n<\/div>\n
\n
Target Antigen: Beta-Tubulin III<\/div>\n<\/div>\n
\n
Alternative Names: CDCBM, CDCBM1, CFEOM3, CFEOM3A, Class III beta-tubulin, FEOM3, TUBB4, Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4 chain<\/div>\n<\/div>\n
\n
Reactive Species: Human; Mouse; Other; Rat<\/div>\n<\/div>\n
\n
Conjugation: Unconjugated<\/div>\n<\/div>\n
\n
Host Species: Mouse<\/div>\n<\/div>\n
\n
Cell Type: Neural Cells, PSC-Derived; Neurons<\/div>\n<\/div>\n
\n
Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting<\/div>\n<\/div>\n
\n
Area of Interest: Neuroscience; Stem Cell Biology<\/div>\n<\/div>\n
\n
Clone: TUJ1<\/div>\n<\/div>\n
\n
Gene ID: 10381<\/div>\n<\/div>\n
\n
Isotype: IgG2a, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  Overview The TUJ1 antibody reacts with beta-tubulin III, an ~50 – 55 kDa structural protein that is a component of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha and beta tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The TUJ1 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the C-terminal 15 amino acids of the protein. Subtype: Primary Antibodies Target Antigen: Beta-Tubulin III Alternative Names: CDCBM, CDCBM1, CFEOM3, CFEOM3A, Class III beta-tubulin, FEOM3, TUBB4, Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4 chain Reactive Species: Human; Mouse; Other; Rat Conjugation: Unconjugated Host Species: Mouse Cell Type: Neural Cells, PSC-Derived; Neurons Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting Area of Interest: Neuroscience; Stem Cell Biology Clone: TUJ1 Gene ID: 10381 Isotype: IgG2a, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2607","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2607"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2607"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2607"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}