{"id":2612,"date":"2020-11-17T11:33:20","date_gmt":"2020-11-17T11:33:20","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2612"},"modified":"2020-11-17T11:33:20","modified_gmt":"2020-11-17T11:33:20","slug":"anti-human-beta-tubulin-iii-antibody-clone-2g10-tb3-mouse-monoclonal-igg2a-antibody-against-human-mouse-rat-betatubulin-iii","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-beta-tubulin-iii-antibody-clone-2g10-tb3-mouse-monoclonal-igg2a-antibody-against-human-mouse-rat-betatubulin-iii\/","title":{"rendered":"Anti-Human Beta-Tubulin III Antibody, Clone 2G10-TB3 Mouse monoclonal IgG2a antibody against human, mouse, rat beta\u00adtubulin III"},"content":{"rendered":"

\"\"<\/h3>\n

Overview<\/h3>\n
\n
\n
The 2G10-TB3 antibody reacts with beta-tubulin III, an ~50 – 55 kDa structural protein that is a constituent of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha- and beta-tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The 2G10-TB3 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the extreme C-terminal amino acids, EAQGPK.<\/div>\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n
\n
\n
\n
Subtype: Primary Antibodies<\/div>\n<\/div>\n
\n
Target Antigen: Beta-Tubulin III<\/div>\n<\/div>\n
\n
Alternative Names: Class 3 beta-tubulin, class III beta-tubulin, MC1R, neuron-specific class 3 beta-tubulin, neuron-specific class III beta-tubulin, TUBB 3, TUBB3, tubulin beta 3, tubulin beta 4, tubulin beta III<\/div>\n<\/div>\n
\n
Reactive Species: Human; Mouse; Rat<\/div>\n<\/div>\n
\n
Conjugation: Unconjugated<\/div>\n<\/div>\n
\n
Host Species: Mouse<\/div>\n<\/div>\n
\n
Cell Type: Neural Cells, PSC-Derived; Neurons<\/div>\n<\/div>\n
\n
Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting<\/div>\n<\/div>\n
\n
Area of Interest: Neuroscience<\/div>\n<\/div>\n
\n
Clone: 2G10-TB3<\/div>\n<\/div>\n
\n
Gene ID: 10381<\/div>\n<\/div>\n
\n
Isotype: IgG2a, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview The 2G10-TB3 antibody reacts with beta-tubulin III, an ~50 – 55 kDa structural protein that is a constituent of tubulin. Tubulin is the major component of microtubules within the cytoskeleton and is assembled from heterodimers of alpha- and beta-tubulin subunits. The beta III isoform of tubulin, also known as neuron-specific class III beta-tubulin, is expressed primarily in neurons and is widely used as a marker to distinguish neurons from other cell types. Beta-tubulin III contributes to microtubule formation in neuronal cell bodies and axons, a function involving GTP binding, and plays roles in axonal transport, neuronal cell proliferation, and differentiation. It is highly expressed in several types of cancer and is a predictive and prognostic marker for various tumors, for example, being found in neoplastic but not in normal glial cells. The 2G10-TB3 antibody is expected to recognize all mammalian homologs of beta-tubulin III and the epitope has reportedly been mapped to the extreme C-terminal amino acids, EAQGPK. Subtype: Primary Antibodies Target Antigen: Beta-Tubulin III Alternative Names: Class 3 beta-tubulin, class III beta-tubulin, MC1R, neuron-specific class 3 beta-tubulin, neuron-specific class III beta-tubulin, TUBB 3, TUBB3, tubulin beta 3, tubulin beta 4, tubulin beta III Reactive Species: Human; Mouse; Rat Conjugation: Unconjugated Host Species: Mouse Cell Type: Neural Cells, PSC-Derived; Neurons Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting Area of Interest: Neuroscience Clone: 2G10-TB3 Gene ID: 10381 Isotype: IgG2a, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2612","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2612"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2612"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2612"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}