{"id":2619,"date":"2020-11-17T13:52:45","date_gmt":"2020-11-17T13:52:45","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&#038;p=2619"},"modified":"2020-11-17T13:52:45","modified_gmt":"2020-11-17T13:52:45","slug":"anti-human-cd138-syndecan-1-antibody-clone-mi15-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd138-syndecan-1","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd138-syndecan-1-antibody-clone-mi15-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd138-syndecan-1\/","title":{"rendered":"Anti-Human CD138 (Syndecan-1) Antibody, Clone MI15 Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD138 (syndecan-1)"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-2579\" src=\"https:\/\/mira-lab.com\/wp-content\/uploads\/2020\/11\/100-0285-product-1.jpg\" alt=\"\" width=\"326\" height=\"251\" srcset=\"https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1.jpg 800w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-270x208.jpg 270w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-570x438.jpg 570w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-320x246.jpg 320w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-768x590.jpg 768w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-540x415.jpg 540w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-1-600x461.jpg 600w\" sizes=\"auto, (max-width: 326px) 100vw, 326px\" \/> <img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-2577\" src=\"https:\/\/mira-lab.com\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg\" alt=\"\" width=\"324\" height=\"249\" srcset=\"https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg 800w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-270x208.jpg 270w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-570x438.jpg 570w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-320x246.jpg 320w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-768x590.jpg 768w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-540x415.jpg 540w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-600x461.jpg 600w\" sizes=\"auto, (max-width: 324px) 100vw, 324px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h3 class=\"sub-title\">Overview<\/h3>\n<div class=\"row\">\n<div class=\"long-description grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div class=\"std\">The MI15 antibody reacts with an extracellular epitope on CD138 (Syndecan-1), an ~85 &#8211; 95 kDa type 1 transmembrane glycoprotein expressed on the surface of pre-B cells, immature B cells, and normal and malignant plasma cells (but not mature circulating B cells), as well as on non-hematopoietic cells such as embryonic mesenchymal cells, endothelial, epithelial and neural cells. CD138 expression is used as a diagnostic marker for several types of tumors. CD138 is thought to act primarily as a receptor that modulates cell proliferation, cell migration and cell-matrix associations by linking the extracellular matrix to the cytoskeleton. Heparin sulfate and chondroitin sulfate moieties attached to CD138 associate with several proteins, including collagens, fibronectin, tenascin, thrombospondin and certain cytokines. The MI15 antibody recognizes a different epitope than that of the clone DL-101 anti-CD138 antibody but blocks binding of clone B-B4.<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div><\/div>\n<div>\n<div class=\"product-attributes grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div id=\"attribute-list\" class=\"table\">\n<div class=\"tbody\">\n<div class=\"tr attr_subtype\">\n<div class=\"th\">Subtype: Primary Antibodies<\/div>\n<\/div>\n<div class=\"tr attr_target_antigen\">\n<div class=\"th\">Target Antigen: CD138 (Syndecan-1)<\/div>\n<\/div>\n<div class=\"tr attr_alternative_names\">\n<div class=\"th\">Alternative Names: B-B4, SDC1, syndecan-1<\/div>\n<\/div>\n<div class=\"tr attr_reactive_species\">\n<div class=\"th\">Reactive Species: Human; Rhesus; Cynomolgus<\/div>\n<\/div>\n<div class=\"tr attr_conjugation\">\n<div class=\"th\">Conjugation: APC; FITC; PE; Unconjugated<\/div>\n<\/div>\n<div class=\"tr attr_host_species\">\n<div class=\"th\">Host Species: Mouse<\/div>\n<\/div>\n<div class=\"tr attr_cell_type\">\n<div class=\"th\">Cell Type: B Cells; Plasma Cells<\/div>\n<\/div>\n<div class=\"tr attr_application\">\n<div class=\"th\">Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting<\/div>\n<\/div>\n<div class=\"tr attr_area_of_interest\">\n<div class=\"th\">Area of Interest: Cancer Research; Immunology<\/div>\n<\/div>\n<div class=\"tr attr_clone\">\n<div class=\"th\">Clone: MI15<\/div>\n<\/div>\n<div class=\"tr attr_gene_id\">\n<div class=\"th\">Gene ID: 6382<\/div>\n<\/div>\n<div class=\"tr attr_isotype\">\n<div class=\"th\">Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Overview The MI15 antibody reacts with an extracellular epitope on CD138 (Syndecan-1), an ~85 &#8211; 95 kDa type 1 transmembrane glycoprotein expressed on the surface of pre-B cells, immature B cells, and normal and malignant plasma cells (but not mature circulating B cells), as well as on non-hematopoietic cells such as embryonic mesenchymal cells, endothelial, epithelial and neural cells. CD138 expression is used as a diagnostic marker for several types of tumors. CD138 is thought to act primarily as a receptor that modulates cell proliferation, cell migration and cell-matrix associations by linking the extracellular matrix to the cytoskeleton. Heparin sulfate and chondroitin sulfate moieties attached to CD138 associate with several proteins, including collagens, fibronectin, tenascin, thrombospondin and certain cytokines. The MI15 antibody recognizes a different epitope than that of the clone DL-101 anti-CD138 antibody but blocks binding of clone B-B4. Subtype: Primary Antibodies Target Antigen: CD138 (Syndecan-1) Alternative Names: B-B4, SDC1, syndecan-1 Reactive Species: Human; Rhesus; Cynomolgus Conjugation: APC; FITC; PE; Unconjugated Host Species: Mouse Cell Type: B Cells; Plasma Cells Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting Area of Interest: Cancer Research; Immunology Clone: MI15 Gene ID: 6382 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2579,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2619","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2619","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2579"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2619"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2619"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2619"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2619"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}