{"id":2627,"date":"2020-11-17T14:43:24","date_gmt":"2020-11-17T14:43:24","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2627"},"modified":"2020-11-17T14:43:24","modified_gmt":"2020-11-17T14:43:24","slug":"anti-human-cd235ab-glycophorin-a-b-antibody-clone-hir2-mouse-monoclonal-igg2b-antibody-against-human-cd235ab-glycophorin-a-b","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd235ab-glycophorin-a-b-antibody-clone-hir2-mouse-monoclonal-igg2b-antibody-against-human-cd235ab-glycophorin-a-b\/","title":{"rendered":"Anti-Human CD235ab (Glycophorin A\/B) Antibody, Clone HIR2 Mouse monoclonal IgG2b antibody against human CD235ab (glycophorin A\/B)"},"content":{"rendered":"

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Overview<\/h3>\n
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The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups. CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types. CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component. The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation. The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD235ab (Glycophorin A\/B)<\/div>\n<\/div>\n
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Alternative Names: CD235a, CD235ab, CD235b, Glycophorin A, Glycophorin B, GPA, GPB, GYPA, GYPB, MN sialoglycoprotein, PAS-2, PAS-3, Sialoglycoprotein alpha, Sialoglycoprotein delta, SS-active sialoglycoprotein<\/div>\n<\/div>\n
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Reactive Species: Human<\/div>\n<\/div>\n
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Conjugation: APC; Biotin; FITC; PE; Unconjugated<\/div>\n<\/div>\n
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Host Species: Mouse<\/div>\n<\/div>\n
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Cell Type: Red Blood Cells<\/div>\n<\/div>\n
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Application: Flow Cytometry; Immunofluorescence; Immunocytochemistry; Immunohistochemistry; Immunoprecipitation; CyTOF; Western Blotting<\/div>\n<\/div>\n
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Area of Interest: Immunology<\/div>\n<\/div>\n
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Clone: HIR2 (GA-R2)<\/div>\n<\/div>\n
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Gene ID: 2993\/2994<\/div>\n<\/div>\n
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Isotype: IgG2b, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  Overview The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups. CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types. CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component. The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation. The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes. Subtype: Primary Antibodies Target Antigen: CD235ab (Glycophorin A\/B) Alternative Names: CD235a, CD235ab, CD235b, Glycophorin A, Glycophorin B, GPA, GPB, GYPA, GYPB, MN sialoglycoprotein, PAS-2, PAS-3, Sialoglycoprotein alpha, Sialoglycoprotein delta, SS-active sialoglycoprotein Reactive Species: Human Conjugation: APC; Biotin; FITC; PE; Unconjugated Host Species: Mouse Cell Type: Red Blood Cells Application: Flow Cytometry; Immunofluorescence; Immunocytochemistry; Immunohistochemistry; Immunoprecipitation; CyTOF; Western Blotting Area of Interest: Immunology Clone: HIR2 (GA-R2) Gene ID: 2993\/2994 Isotype: IgG2b, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2627","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2627","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2627"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2627"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2627"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2627"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}