{"id":2629,"date":"2020-11-17T14:53:19","date_gmt":"2020-11-17T14:53:19","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2629"},"modified":"2020-11-17T14:53:19","modified_gmt":"2020-11-17T14:53:19","slug":"anti-human-cd25-antibody-clone-2a3-mouse-monoclonal-igg1-antibody-against-human-cynomolgus-cd25","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd25-antibody-clone-2a3-mouse-monoclonal-igg1-antibody-against-human-cynomolgus-cd25\/","title":{"rendered":"Anti-Human CD25 Antibody, Clone 2A3 Mouse monoclonal IgG1 antibody against human, cynomolgus CD25"},"content":{"rendered":"

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Overview<\/h3>\n
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The 2A3 antibody reacts with human CD25, a 55 kDa type I integral transmembrane glycoprotein also known as low-affinity interleukin 2 receptor alpha chain (IL-2R\u03b1) or Tac antigen. CD25 is present on activated T and B cells, monocytes, macrophages, and regulatory T cells. CD25 has a role in T lymphocyte activation and can be used in the identification of T cell subsets in viral infections like HIV and HTLV. CD25 associates with IL-2 receptor \u03b2 (CD122) and common \u03b3 (CD132) chains to form a high-affinity IL-2R complex. The 2A3 antibody binds to an epitope on p55 at or near the IL-2 binding site and prevents high-affinity IL-2 binding to T lymphocytes. Daclizumab, a therapeutic humanized monoclonal antibody, blocks the binding of 2A3 antibody.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD25<\/div>\n<\/div>\n
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Alternative Names: IL-R2\u03b1, Interleukin 2 receptor alpha, Low affinity IL-2R, p55, Tac<\/div>\n<\/div>\n
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Reactive Species: Cynomolgus; Human<\/div>\n<\/div>\n
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Conjugation: PE<\/div>\n<\/div>\n
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Host Species: Mouse<\/div>\n<\/div>\n
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Cell Type: T Cells; T Cells, Regulatory<\/div>\n<\/div>\n
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Application: Cell Isolation; Flow Cytometry<\/div>\n<\/div>\n
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Area of Interest: Immunology; Cell Therapy<\/div>\n<\/div>\n
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Clone: 2A3<\/div>\n<\/div>\n
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Gene ID: 100<\/div>\n<\/div>\n
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Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  Overview The 2A3 antibody reacts with human CD25, a 55 kDa type I integral transmembrane glycoprotein also known as low-affinity interleukin 2 receptor alpha chain (IL-2R\u03b1) or Tac antigen. CD25 is present on activated T and B cells, monocytes, macrophages, and regulatory T cells. CD25 has a role in T lymphocyte activation and can be used in the identification of T cell subsets in viral infections like HIV and HTLV. CD25 associates with IL-2 receptor \u03b2 (CD122) and common \u03b3 (CD132) chains to form a high-affinity IL-2R complex. The 2A3 antibody binds to an epitope on p55 at or near the IL-2 binding site and prevents high-affinity IL-2 binding to T lymphocytes. Daclizumab, a therapeutic humanized monoclonal antibody, blocks the binding of 2A3 antibody. Subtype: Primary Antibodies Target Antigen: CD25 Alternative Names: IL-R2\u03b1, Interleukin 2 receptor alpha, Low affinity IL-2R, p55, Tac Reactive Species: Cynomolgus; Human Conjugation: PE Host Species: Mouse Cell Type: T Cells; T Cells, Regulatory Application: Cell Isolation; Flow Cytometry Area of Interest: Immunology; Cell Therapy Clone: 2A3 Gene ID: 100 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2629","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2629"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2629"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2629"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}