{"id":2642,"date":"2020-11-18T10:24:17","date_gmt":"2020-11-18T10:24:17","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2642"},"modified":"2020-11-18T10:24:18","modified_gmt":"2020-11-18T10:24:18","slug":"anti-human-cd34-antibody-clone-563-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd34","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd34-antibody-clone-563-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd34\/","title":{"rendered":"Anti-Human CD34 Antibody, Clone 563 Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD34"},"content":{"rendered":"

\"\"<\/p>\n

Overview<\/h3>\n
\n
\n
CD34 is an ~105 – 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 – 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 563 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 563 also cross-reacts with CD34+ cells of rhesus, cynomolgus, and pigtailed macaques, but not baboons.<\/div>\n<\/div>\n<\/div>\n
<\/div>\n
\n
\n
\n
\n
\n
Subtype: Primary Antibodies<\/div>\n<\/div>\n
\n
Target Antigen: CD34<\/div>\n<\/div>\n
\n
Alternative Names: Gp105-120, My10<\/div>\n<\/div>\n
\n
Reactive Species: Human; Rhesus; Cynomolgus<\/div>\n<\/div>\n
\n
Conjugation: PE<\/div>\n<\/div>\n
\n
Host Species: Mouse<\/div>\n<\/div>\n
\n
Cell Type: Hematopoietic Stem and Progenitor Cells<\/div>\n<\/div>\n
\n
Application: Flow Cytometry; Cell Culture<\/div>\n<\/div>\n
\n
Area of Interest: Stem Cell Biology<\/div>\n<\/div>\n
\n
Clone: 563<\/div>\n<\/div>\n
\n
Gene ID: 947<\/div>\n<\/div>\n
\n
Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview CD34 is an ~105 – 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 – 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 563 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 563 also cross-reacts with CD34+ cells of rhesus, cynomolgus, and pigtailed macaques, but not baboons. Subtype: Primary Antibodies Target Antigen: CD34 Alternative Names: Gp105-120, My10 Reactive Species: Human; Rhesus; Cynomolgus Conjugation: PE Host Species: Mouse Cell Type: Hematopoietic Stem and Progenitor Cells Application: Flow Cytometry; Cell Culture Area of Interest: Stem Cell Biology Clone: 563 Gene ID: 947 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2575,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2642","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2575"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2642"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2642"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2642"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}