{"id":2656,"date":"2020-11-18T14:21:44","date_gmt":"2020-11-18T14:21:44","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2656"},"modified":"2020-11-18T14:21:44","modified_gmt":"2020-11-18T14:21:44","slug":"anti-human-cd5-antibody-clone-ucht2-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd5","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd5-antibody-clone-ucht2-mouse-monoclonal-igg1-antibody-against-human-rhesus-cynomolgus-cd5\/","title":{"rendered":"Anti-Human CD5 Antibody, Clone UCHT2 Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD5"},"content":{"rendered":"

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Overview<\/h3>\n
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The UCHT2 antibody reacts with CD5, an ~67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells. CD5 is expressed at low levels on thymocytes and at high density on mature T cells. Putative ligands include CD5L and CD72. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell\/B cell interactions via its physical and functional associations with the T cell receptor\/CD3 complex and the B cell receptor. Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells. The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD5<\/div>\n<\/div>\n
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Alternative Names: Leu1, Leu-1, Ly-1, Lymphocyte antigen T1, T1, Tp67<\/div>\n<\/div>\n
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Reactive Species: Capuchin Monkey; Common Marmoset; Cynomolgus; Owl Monkey; Rhesus; Chimpanzee; Human<\/div>\n<\/div>\n
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Conjugation: APC; Biotin; FITC; PE; PerCP-Cyanine5.5; Unconjugated<\/div>\n<\/div>\n
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Host Species: Mouse<\/div>\n<\/div>\n
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Cell Type: T Cells<\/div>\n<\/div>\n
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Application: Flow Cytometry; Immunocytochemistry; Immunohistochemistry; Western Blotting<\/div>\n<\/div>\n
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Area of Interest: Immunology; Stem Cell Biology<\/div>\n<\/div>\n
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Clone: UCHT2<\/div>\n<\/div>\n
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Gene ID: 921<\/div>\n<\/div>\n
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Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview The UCHT2 antibody reacts with CD5, an ~67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells. CD5 is expressed at low levels on thymocytes and at high density on mature T cells. Putative ligands include CD5L and CD72. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell\/B cell interactions via its physical and functional associations with the T cell receptor\/CD3 complex and the B cell receptor. Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells. The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5. Subtype: Primary Antibodies Target Antigen: CD5 Alternative Names: Leu1, Leu-1, Ly-1, Lymphocyte antigen T1, T1, Tp67 Reactive Species: Capuchin Monkey; Common Marmoset; Cynomolgus; Owl Monkey; Rhesus; Chimpanzee; Human Conjugation: APC; Biotin; FITC; PE; PerCP-Cyanine5.5; Unconjugated Host Species: Mouse Cell Type: T Cells Application: Flow Cytometry; Immunocytochemistry; Immunohistochemistry; Western Blotting Area of Interest: Immunology; Stem Cell Biology Clone: UCHT2 Gene ID: 921 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2656","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2656"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2656"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2656"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}