{"id":2659,"date":"2020-11-19T09:08:30","date_gmt":"2020-11-19T09:08:30","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2659"},"modified":"2020-11-19T09:08:30","modified_gmt":"2020-11-19T09:08:30","slug":"anti-human-cd66b-antibody-clone-g10f5-mouse-monoclonal-igm-antibody-against-human-chimpanzee-cd66b","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-human-cd66b-antibody-clone-g10f5-mouse-monoclonal-igm-antibody-against-human-chimpanzee-cd66b\/","title":{"rendered":"Anti-Human CD66b Antibody, Clone G10F5 Mouse monoclonal IgM antibody against human, chimpanzee CD66b"},"content":{"rendered":"

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Overview<\/h3>\n
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The G10F5 antibody reacts with CD66b (previously denoted CD67), an ~95 kDa single-chain glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed by neutrophilic and eosinophilic granulocytes. CD66b is a member of the carcinoembryonic antigen (CEA)-like subfamily of proteins within the immunoglobulin superfamily and possesses two Ig-like C2-type domains and one Ig-like V-type domain. In neutrophils, CD66b is localized within granules in the cytoplasm as well as being expressed on the plasma membrane. Surface expression levels increase upon granulocyte activation, an effect induced by stimulators such as phorbol myristate acetate (PMA), calcium ionophore, and N-formylmethionyl-leucyl-phenylalanine (FMLP). CD66b appears to play a role as a signaling receptor involved in cell adhesion, phagocytosis, and chemotaxis by regulating granulocyte activation and adhesion to several proteins, including CD66c, galectin-3, fibronectin, and E-selectin.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD66b<\/div>\n<\/div>\n
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Alternative Names: Carcinoembryonic antigen-related cell adhesion molecule 8, CD67, CEACAM8, CGM6, NCA-95<\/div>\n<\/div>\n
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Reactive Species: Chimpanzee; Human<\/div>\n<\/div>\n
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Conjugation: APC; FITC; PE; Unconjugated; Pacific Blue<\/div>\n<\/div>\n
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Host Species: Mouse<\/div>\n<\/div>\n
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Cell Type: Granulocytes and Subsets; Myeloid Cells<\/div>\n<\/div>\n
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Application: Functional Assay; Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting<\/div>\n<\/div>\n
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Area of Interest: Immunology<\/div>\n<\/div>\n
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Clone: G10F5<\/div>\n<\/div>\n
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Gene ID: 1088<\/div>\n<\/div>\n
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Isotype: IgM, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  Overview The G10F5 antibody reacts with CD66b (previously denoted CD67), an ~95 kDa single-chain glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed by neutrophilic and eosinophilic granulocytes. CD66b is a member of the carcinoembryonic antigen (CEA)-like subfamily of proteins within the immunoglobulin superfamily and possesses two Ig-like C2-type domains and one Ig-like V-type domain. In neutrophils, CD66b is localized within granules in the cytoplasm as well as being expressed on the plasma membrane. Surface expression levels increase upon granulocyte activation, an effect induced by stimulators such as phorbol myristate acetate (PMA), calcium ionophore, and N-formylmethionyl-leucyl-phenylalanine (FMLP). CD66b appears to play a role as a signaling receptor involved in cell adhesion, phagocytosis, and chemotaxis by regulating granulocyte activation and adhesion to several proteins, including CD66c, galectin-3, fibronectin, and E-selectin. Subtype: Primary Antibodies Target Antigen: CD66b Alternative Names: Carcinoembryonic antigen-related cell adhesion molecule 8, CD67, CEACAM8, CGM6, NCA-95 Reactive Species: Chimpanzee; Human Conjugation: APC; FITC; PE; Unconjugated; Pacific Blue Host Species: Mouse Cell Type: Granulocytes and Subsets; Myeloid Cells Application: Functional Assay; Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunohistochemistry; Immunoprecipitation; Western Blotting Area of Interest: Immunology Clone: G10F5 Gene ID: 1088 Isotype: IgM, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2659","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2659"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2659"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2659"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}