{"id":2732,"date":"2020-11-30T09:57:10","date_gmt":"2020-11-30T09:57:10","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2732"},"modified":"2020-11-30T09:57:11","modified_gmt":"2020-11-30T09:57:11","slug":"anti-mouse-cd16-cd32-antibody-clone-2-4g2-rat-monoclonal-igg2b-antibody-against-mouse-cd16-cd32","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-mouse-cd16-cd32-antibody-clone-2-4g2-rat-monoclonal-igg2b-antibody-against-mouse-cd16-cd32\/","title":{"rendered":"Anti-Mouse CD16\/CD32 Antibody, Clone 2.4G2 Rat monoclonal IgG2b antibody against mouse CD16\/CD32"},"content":{"rendered":"

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Overview<\/h3>\n
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The 2.4G2 antibody reacts with a shared epitope of Fc-gamma receptors CD16 (FcRIII) and CD32 (FcRII) in the mouse. CD16 and CD32 are low affinity receptors for the Fc portion of IgG, with CD32 having a higher affinity for IgG aggregates and immune complexes. CD16 and CD32 are expressed on B cells, monocytes, macrophages, NK cells, neutrophils, granulocytes, mast cells, and dendritic cells. The binding of immunoglobulins to Fc receptors is involved in multiple immunological functions, including phagocytosis, cytotoxocity, and the modulation of immune responses. The 2.4G2 antibody blocks the interaction between IgG and CD16 or CD32, and therefore is used as a pre-treatment to minimize non-specific binding of antibodies to FcR-bearing cells in applications such as flow cytometry, cell sorting, and immunofluorescence.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: CD16\/CD32<\/div>\n<\/div>\n
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Alternative Names: FCGR2, FCGR3, FC Receptor, IGFR2, IGFR3, Ly-17<\/div>\n<\/div>\n
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Reactive Species: Mouse<\/div>\n<\/div>\n
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Conjugation: FITC; Unconjugated<\/div>\n<\/div>\n
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Host Species: Rat<\/div>\n<\/div>\n
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Cell Type: Dendritic Cells; Granulocytes and Subsets; Monocytes; Myeloid Cells; NK Cells; T Cells; T Cells, Other Subsets; Macrophages<\/div>\n<\/div>\n
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Application: Flow Cytometry; Immunofluorescence; Immunoprecipitation; Functional Assay<\/div>\n<\/div>\n
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Area of Interest: Immunology<\/div>\n<\/div>\n
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Clone: 2.4G2<\/div>\n<\/div>\n
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Gene ID: 14130\/14131<\/div>\n<\/div>\n
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Isotype: IgG2b, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview The 2.4G2 antibody reacts with a shared epitope of Fc-gamma receptors CD16 (FcRIII) and CD32 (FcRII) in the mouse. CD16 and CD32 are low affinity receptors for the Fc portion of IgG, with CD32 having a higher affinity for IgG aggregates and immune complexes. CD16 and CD32 are expressed on B cells, monocytes, macrophages, NK cells, neutrophils, granulocytes, mast cells, and dendritic cells. The binding of immunoglobulins to Fc receptors is involved in multiple immunological functions, including phagocytosis, cytotoxocity, and the modulation of immune responses. The 2.4G2 antibody blocks the interaction between IgG and CD16 or CD32, and therefore is used as a pre-treatment to minimize non-specific binding of antibodies to FcR-bearing cells in applications such as flow cytometry, cell sorting, and immunofluorescence. Subtype: Primary Antibodies Target Antigen: CD16\/CD32 Alternative Names: FCGR2, FCGR3, FC Receptor, IGFR2, IGFR3, Ly-17 Reactive Species: Mouse Conjugation: FITC; Unconjugated Host Species: Rat Cell Type: Dendritic Cells; Granulocytes and Subsets; Monocytes; Myeloid Cells; NK Cells; T Cells; T Cells, Other Subsets; Macrophages Application: Flow Cytometry; Immunofluorescence; Immunoprecipitation; Functional Assay Area of Interest: Immunology Clone: 2.4G2 Gene ID: 14130\/14131 Isotype: IgG2b, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2732","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2732","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2732"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2732"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2732"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2732"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}