{"id":2760,"date":"2020-11-30T12:25:38","date_gmt":"2020-11-30T12:25:38","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&#038;p=2760"},"modified":"2020-11-30T12:25:38","modified_gmt":"2020-11-30T12:25:38","slug":"anti-mouse-e-cadherin-cd324-antibody-clone-decma-1-rat-monoclonal-igg1-antibody-against-human-mouse-dog-ecadherin-cd324","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-mouse-e-cadherin-cd324-antibody-clone-decma-1-rat-monoclonal-igg1-antibody-against-human-mouse-dog-ecadherin-cd324\/","title":{"rendered":"Anti-Mouse E-Cadherin (CD324) Antibody, Clone DECMA-1 Rat monoclonal IgG1 antibody against human, mouse, dog E\u00adcadherin (CD324)"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-2577\" src=\"https:\/\/mira-lab.com\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg\" alt=\"\" width=\"347\" height=\"267\" srcset=\"https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg 800w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-270x208.jpg 270w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-570x438.jpg 570w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-320x246.jpg 320w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-768x590.jpg 768w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-540x415.jpg 540w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-600x461.jpg 600w\" sizes=\"auto, (max-width: 347px) 100vw, 347px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h3 class=\"sub-title\">Overview<\/h3>\n<div class=\"row\">\n<div class=\"long-description grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div class=\"std\">The DECMA-1 antibody recognizes E-cadherin, a calcium-dependent transmembrane glycoprotein involved in cell-cell adhesion, bacterial pathogenesis, and tumor invasion. The extracellular region of E-cadherin is composed of multiple cadherin repeats that contain calcium-binding motifs. The cytoplasmic domain of E-cadherin is reported to interact with a range of intracellular proteins including erbin, ezrin, caspase-3, caspase-8, \u03b2-catenin, presenilin 1, and casein kinase II. E-cadherin is expressed in most epithelial cells and in erythroid cells. The E-cadherin antibody is often used as a neutralizing antibody to inhibit E-cadherin-mediated cell-cell interactions.<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div>\n<div class=\"product-attributes grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div id=\"attribute-list\" class=\"table\">\n<div class=\"tbody\">\n<div class=\"tr attr_subtype\">\n<div class=\"th\">Subtype: Primary Antibodies<\/div>\n<\/div>\n<div class=\"tr attr_target_antigen\">\n<div class=\"th\">Target Antigen: E-Cadherin (CD324)<\/div>\n<\/div>\n<div class=\"tr attr_alternative_names\">\n<div class=\"th\">Alternative Names: Arc 1, Cadherin-1, CAM 120\/80, CDHE, CDH1, E-Cad\/CTF3, Epithelial cadherin, epithelial calcium-dependent adhesion protein, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin<\/div>\n<\/div>\n<div class=\"tr attr_reactive_species\">\n<div class=\"th\">Reactive Species: Human; Mouse; Pig; Dog<\/div>\n<\/div>\n<div class=\"tr attr_conjugation\">\n<div class=\"th\">Conjugation: Unconjugated<\/div>\n<\/div>\n<div class=\"tr attr_host_species\">\n<div class=\"th\">Host Species: Rat<\/div>\n<\/div>\n<div class=\"tr attr_cell_type\">\n<div class=\"th\">Cell Type: Airway Cells<\/div>\n<\/div>\n<div class=\"tr attr_application\">\n<div class=\"th\">Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunoprecipitation; Western Blotting; Functional Assay<\/div>\n<\/div>\n<div class=\"tr attr_area_of_interest\">\n<div class=\"th\">Area of Interest: Endothelial Cell Biology<\/div>\n<\/div>\n<div class=\"tr attr_clone\">\n<div class=\"th\">Clone: DECMA-1<\/div>\n<\/div>\n<div class=\"tr attr_gene_id\">\n<div class=\"th\">Gene ID: 999\/12550<\/div>\n<\/div>\n<div class=\"tr attr_isotype\">\n<div class=\"th\">Isotype: IgG1, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Overview The DECMA-1 antibody recognizes E-cadherin, a calcium-dependent transmembrane glycoprotein involved in cell-cell adhesion, bacterial pathogenesis, and tumor invasion. The extracellular region of E-cadherin is composed of multiple cadherin repeats that contain calcium-binding motifs. The cytoplasmic domain of E-cadherin is reported to interact with a range of intracellular proteins including erbin, ezrin, caspase-3, caspase-8, \u03b2-catenin, presenilin 1, and casein kinase II. E-cadherin is expressed in most epithelial cells and in erythroid cells. The E-cadherin antibody is often used as a neutralizing antibody to inhibit E-cadherin-mediated cell-cell interactions. Subtype: Primary Antibodies Target Antigen: E-Cadherin (CD324) Alternative Names: Arc 1, Cadherin-1, CAM 120\/80, CDHE, CDH1, E-Cad\/CTF3, Epithelial cadherin, epithelial calcium-dependent adhesion protein, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin Reactive Species: Human; Mouse; Pig; Dog Conjugation: Unconjugated Host Species: Rat Cell Type: Airway Cells Application: Flow Cytometry; Immunocytochemistry; Immunofluorescence; Immunoprecipitation; Western Blotting; Functional Assay Area of Interest: Endothelial Cell Biology Clone: DECMA-1 Gene ID: 999\/12550 Isotype: IgG1, kappa<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2760","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2760","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2760"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2760"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2760"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2760"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}