{"id":2761,"date":"2020-11-30T12:27:59","date_gmt":"2020-11-30T12:27:59","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&p=2761"},"modified":"2020-11-30T12:28:42","modified_gmt":"2020-11-30T12:28:42","slug":"anti-mouse-epcr-antibody-clone-rmepcr1560-1560-rat-monoclonal-igg2b-antibody-against-mouse-epcr-cd201","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-mouse-epcr-antibody-clone-rmepcr1560-1560-rat-monoclonal-igg2b-antibody-against-mouse-epcr-cd201\/","title":{"rendered":"Anti-Mouse EPCR Antibody, Clone RMEPCR1560 (1560) Rat monoclonal IgG2b antibody against mouse EPCR (CD201)"},"content":{"rendered":"

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Overview<\/h3>\n
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The RMEPCR1560 (1560) antibody reacts with the endothelial protein C receptor (EPCR or CD201), an ~25 kDa type I transmembrane glycoprotein expressed by endothelial cells, subsets of hematopoietic stem cells (HSCs) and dendritic cells, and several malignant cell lines. It is also found in a soluble form in plasma. EPCR exhibits homology with the MHC class 1\/CD1 protein family. EPCR binds protein C and activated protein C, thus augmenting protein C activation by the thrombin-thrombomodulin complex and regulating blood coagulation and inflammation. EPCR protein expression has been detected on ~1.5% of mouse bone marrow cells. Purified EPCR+ cells are highly enriched for HSC activity, as evidenced by high in vivo repopulation activity. Moreover, EPCR expression is associated with the stem cell activity of bone marrow cell populations isolated using conventional markers, indicating the usefulness of EPCR as a single marker for the identification of mouse HSCs.<\/div>\n<\/div>\n<\/div>\n
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Subtype: Primary Antibodies<\/div>\n<\/div>\n
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Target Antigen: EPCR (CD201)<\/div>\n<\/div>\n
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Alternative Names: Activated protein C receptor, APC receptor, CCD41, CD201, endothelial protein C receptor, PROCR, protein C receptor<\/div>\n<\/div>\n
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Reactive Species: Mouse<\/div>\n<\/div>\n
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Conjugation: Biotin; FITC; PE; Unconjugated<\/div>\n<\/div>\n
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Host Species: Rat<\/div>\n<\/div>\n
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Cell Type: Hematopoietic Stem and Progenitor Cells; Endothelial Cells<\/div>\n<\/div>\n
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Application: Cell Isolation; Flow Cytometry; Functional Assay; Immunohistochemistry; Western Blotting<\/div>\n<\/div>\n
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Area of Interest: Stem Cell Biology; Endothelial Cell Biology<\/div>\n<\/div>\n
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Clone: RMEPCR1560 (1560)<\/div>\n<\/div>\n
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Gene ID: 19124<\/div>\n<\/div>\n
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Isotype: IgG2b, kappa<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

  Overview The RMEPCR1560 (1560) antibody reacts with the endothelial protein C receptor (EPCR or CD201), an ~25 kDa type I transmembrane glycoprotein expressed by endothelial cells, subsets of hematopoietic stem cells (HSCs) and dendritic cells, and several malignant cell lines. It is also found in a soluble form in plasma. EPCR exhibits homology with the MHC class 1\/CD1 protein family. EPCR binds protein C and activated protein C, thus augmenting protein C activation by the thrombin-thrombomodulin complex and regulating blood coagulation and inflammation. EPCR protein expression has been detected on ~1.5% of mouse bone marrow cells. Purified EPCR+ cells are highly enriched for HSC activity, as evidenced by high in vivo repopulation activity. Moreover, EPCR expression is associated with the stem cell activity of bone marrow cell populations isolated using conventional markers, indicating the usefulness of EPCR as a single marker for the identification of mouse HSCs. Subtype: Primary Antibodies Target Antigen: EPCR (CD201) Alternative Names: Activated protein C receptor, APC receptor, CCD41, CD201, endothelial protein C receptor, PROCR, protein C receptor Reactive Species: Mouse Conjugation: Biotin; FITC; PE; Unconjugated Host Species: Rat Cell Type: Hematopoietic Stem and Progenitor Cells; Endothelial Cells Application: Cell Isolation; Flow Cytometry; Functional Assay; Immunohistochemistry; Western Blotting Area of Interest: Stem Cell Biology; Endothelial Cell Biology Clone: RMEPCR1560 (1560) Gene ID: 19124 Isotype: IgG2b, kappa<\/p>\n","protected":false},"featured_media":2537,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2761","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2761","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2537"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2761"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2761"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2761"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2761"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}