{"id":2781,"date":"2020-12-01T12:26:53","date_gmt":"2020-12-01T12:26:53","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&#038;p=2781"},"modified":"2020-12-01T12:26:53","modified_gmt":"2020-12-01T12:26:53","slug":"anti-ship-c-terminus-antibody-polyclonal-rabbit-polyclonal-antibody-against-human-mouse-ship","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/anti-ship-c-terminus-antibody-polyclonal-rabbit-polyclonal-antibody-against-human-mouse-ship\/","title":{"rendered":"Anti-SHIP (C-Terminus) Antibody, Polyclonal Rabbit polyclonal antibody against human, mouse SHIP"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-2577\" src=\"https:\/\/mira-lab.com\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg\" alt=\"\" width=\"388\" height=\"298\" srcset=\"https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2.jpg 800w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-270x208.jpg 270w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-570x438.jpg 570w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-320x246.jpg 320w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-768x590.jpg 768w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-540x415.jpg 540w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2020\/11\/100-0285-product-2-600x461.jpg 600w\" sizes=\"auto, (max-width: 388px) 100vw, 388px\" \/><\/p>\n<h3 class=\"sub-title\">Overview<\/h3>\n<div class=\"row\">\n<div class=\"long-description grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div class=\"std\">SHIP (C-terminus) is critical for the function of SHIP protein. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div>\n<div class=\"product-attributes grid_6_lg grid_6_md grid_6_sm grid_12_sm\">\n<div id=\"attribute-list\" class=\"table\">\n<div class=\"tbody\">\n<div class=\"tr attr_subtype\">\n<div class=\"th\">Subtype: Primary Antibodies<\/div>\n<\/div>\n<div class=\"tr attr_target_antigen\">\n<div class=\"th\">Target Antigen: SHIP<\/div>\n<\/div>\n<div class=\"tr attr_alternative_names\">\n<div class=\"th\">Alternative Names: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145<\/div>\n<\/div>\n<div class=\"tr attr_reactive_species\">\n<div class=\"th\">Reactive Species: Mouse; Human<\/div>\n<\/div>\n<div class=\"tr attr_conjugation\">\n<div class=\"th\">Conjugation: Unconjugated<\/div>\n<\/div>\n<div class=\"tr attr_host_species\">\n<div class=\"th\">Host Species: Rabbit<\/div>\n<\/div>\n<div class=\"tr attr_cell_type\">\n<div class=\"th\">Cell Type: Granulocytes and Subsets; Lymphocytes; Myeloid Cells<\/div>\n<\/div>\n<div class=\"tr attr_application\">\n<div class=\"th\">Application: Immunoblotting; Immunoprecipitation<\/div>\n<\/div>\n<div class=\"tr attr_area_of_interest\">\n<div class=\"th\">Area of Interest: Immunology<\/div>\n<\/div>\n<div class=\"tr attr_clone\">\n<div class=\"th\">Clone: Not applicable<\/div>\n<\/div>\n<div class=\"tr attr_gene_id\">\n<div class=\"th\">Gene ID: 3635 (human), 16331 (mouse)<\/div>\n<\/div>\n<div class=\"tr attr_isotype\">\n<div class=\"th\">Isotype: Not applicable<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Overview SHIP (C-terminus) is critical for the function of SHIP protein. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein. Subtype: Primary Antibodies Target Antigen: SHIP Alternative Names: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145 Reactive Species: Mouse; Human Conjugation: Unconjugated Host Species: Rabbit Cell Type: Granulocytes and Subsets; Lymphocytes; Myeloid Cells Application: Immunoblotting; Immunoprecipitation Area of Interest: Immunology Clone: Not applicable Gene ID: 3635 (human), 16331 (mouse) Isotype: Not applicable<\/p>\n","protected":false},"featured_media":2577,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[138],"product_tag":[],"class_list":["post-2781","product","type-product","status-publish","has-post-thumbnail","product_cat-antibodies","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/2781","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/2577"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=2781"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=2781"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=2781"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=2781"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}