{"id":3138,"date":"2021-03-06T13:55:39","date_gmt":"2021-03-06T13:55:39","guid":{"rendered":"https:\/\/mira-lab.com\/?post_type=product&#038;p=3138"},"modified":"2021-03-06T13:55:39","modified_gmt":"2021-03-06T13:55:39","slug":"krumdieck-tissue-slicer","status":"publish","type":"product","link":"https:\/\/mira-lab.com\/new\/product\/krumdieck-tissue-slicer\/","title":{"rendered":"Krumdieck Tissue Slicer"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-3139\" src=\"https:\/\/mira-lab.com\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440.png\" alt=\"\" width=\"700\" height=\"440\" srcset=\"https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440.png 700w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440-270x170.png 270w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440-570x358.png 570w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440-320x201.png 320w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440-540x339.png 540w, https:\/\/mira-lab.com\/new\/wp-content\/uploads\/2021\/03\/Alabama-RD-MD6000-Photo-freigestellt-700x440-600x377.png 600w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><\/p>\n<p>The instrument provides samples of uniform and reproducible thickness, minimizes damage to surfaces of slices and thereby eliminates the main sources of error in tissue slice work. Slices from approximately 100 to 500 microns in thickness can be prepared at a maximum rate of one slice every 3 to 4 seconds. The slicer operates submerged in a buffer selected by the operator as most appropriate in terms of composition, tonicity, pH, temperature, oxygenation, and lubricating properties to maintain the viability of the tissues being sectioned. The microtome and the reservoir with the glass trap are sterilizable to allow the preparation of aseptic slices suitable for prolonged organ culture. The actual slicing is done by a rapidly reciprocating disposable blade oscillating at 1000 to 2500 rpm driven by a motor that also powers the impeller. The tissue slicer contains a cooling block which allows the temperature of the buffer solution in the slicer\u2019s reservoir to be maintained.<\/p>\n<div class=\"tab_content\">\n<div class=\"tabs_tab\">\n<p class=\"c-bibliographic-information__citation\">Kim, K.H., Kim, J., Han, J.Y.\u00a0<i>et al.<\/i>\u00a0<i>In vitro<\/i>\u00a0estimation of metal-induced disturbance in chicken gut-oviduct chemokine circuit.\u00a0<i>Mol. Cell. Toxicol.<\/i>\u00a015<b>,\u00a0<\/b>443\u2013452 (2019).<\/p>\n<p>Ramzan, A.A., Bitler, B.G., Hicks, D.\u00a0<i>et al.<\/i>\u00a0Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells.\u00a0<i>Mol Cell Biochem<\/i>\u00a0461<b>,\u00a0<\/b>37\u201346 (2019).<\/p>\n<p>Fu, Y., Tong, J., Meng, F.\u00a0<i>et al.<\/i>\u00a0Ciliostasis of airway epithelial cells facilitates influenza A virus infection.\u00a0<i>Vet Res<\/i>\u00a049<b>,\u00a0<\/b>65 (2018).<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The instrument provides samples of uniform and reproducible thickness, minimizes damage to surfaces of slices and thereby eliminates the main sources of error in tissue slice work. Slices from approximately 100 to 500 microns in thickness can be prepared at a maximum rate of one slice every 3 to 4 seconds. The slicer operates submerged in a buffer selected by the operator as most appropriate in terms of composition, tonicity, pH, temperature, oxygenation, and lubricating properties to maintain the viability of the tissues being sectioned. The microtome and the reservoir with the glass trap are sterilizable to allow the preparation of aseptic slices suitable for prolonged organ culture. The actual slicing is done by a rapidly reciprocating disposable blade oscillating at 1000 to 2500 rpm driven by a motor that also powers the impeller. The tissue slicer contains a cooling block which allows the temperature of the buffer solution in the slicer\u2019s reservoir to be maintained. Kim, K.H., Kim, J., Han, J.Y.\u00a0et al.\u00a0In vitro\u00a0estimation of metal-induced disturbance in chicken gut-oviduct chemokine circuit.\u00a0Mol. Cell. Toxicol.\u00a015,\u00a0443\u2013452 (2019). Ramzan, A.A., Bitler, B.G., Hicks, D.\u00a0et al.\u00a0Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells.\u00a0Mol Cell Biochem\u00a0461,\u00a037\u201346 (2019). Fu, Y., Tong, J., Meng, F.\u00a0et al.\u00a0Ciliostasis of airway epithelial cells facilitates influenza A virus infection.\u00a0Vet Res\u00a049,\u00a065 (2018).<\/p>\n","protected":false},"featured_media":3139,"template":"","meta":{"nf_dc_page":""},"product_brand":[],"product_cat":[181],"product_tag":[],"class_list":["post-3138","product","type-product","status-publish","has-post-thumbnail","product_cat-physiology-products","cms-has-post-thumbnail","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product\/3138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media\/3139"}],"wp:attachment":[{"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/media?parent=3138"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_brand?post=3138"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_cat?post=3138"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/mira-lab.com\/new\/wp-json\/wp\/v2\/product_tag?post=3138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}