Overview
The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II antigen encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein composed of one α (36 kDa) and one β (27 kDa) subunit. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T cells.
Subtype: Primary Antibodies
Target Antigen: HLA-DR
Alternative Names: HLA class II histocompatibility antigen, HLA-DR alpha, HLA-DRA, HLA DRA1, HLA DR1B, HLA DR3B, HLA DRB1, HLA DRB3, HLA DRB4, HLA DRB5, HLADR4B, HLADRA1, HLADRB, Major histocompatibility class II, MHC II, MHC class II, MHC class II antigen DRA, MLRW
Reactive Species: Human; Rhesus
Conjugation: FITC; PE; Unconjugated; Alexa Fluor 488
Host Species: Mouse
Cell Type: B Cells; Dendritic Cells; Monocytes; T Cells; Other; Macrophages
Application: Flow Cytometry; Immunohistochemistry; Functional Assay
Area of Interest: HLA; Immunology; Transplantation Research; Infectious Diseases
Clone: LN3
Gene ID: 3122/3123
Isotype: IgG2b, kappa
