Lupus anticoagulant is a group of similar inhibitors of coagulation system, which belong to antibodies IgM or IgG. In practice presence of
lupus anticoagulant is connected with thrombosis of different aetiology (rheumatoid arthritis) and availability of different pregnancy pathology, that
leads to miscarriage, syndrome of development delay, mortinatality. Lupus anticoagulant is defined as antibody, which inhibit phospholipid –
depended coagulation tests in absence of specific inhibitors of coagulation factors. Principle. Lupus anticoagulant (LA) is the nonspecific inhibitor of phospholipid dependent
clotting tests. Screening tests (APTT, PT, RR) show clotting time elongation, adding normal plasma do not normalize clotting, clotting time shorten after
the same tests assay with phospholipids show LA.
LA-TEST
The kit of reagents for the determination of lupus anticoagulant.
Cat. # LE-1 for 40-80 assays.
Reagents:
APTT-reagents:
– APTTc (3 mL), lyophilised – 2 vials
– APTTp (2 mL), lyophilised – 2 vials
Russel reagents:
– RRc (2 mL) lyophilised – 2 vials
– RRp (1 mL) lyophilised – 2 vials
PT reagents:
– PTc (1 mL) lyophilised – 1 vial
– PTp (4 mL) lyophilised – 1 vial
